A Pediatric Cluster of Shigella dysenteriae Serotype 1 Diarrhea with Hemolytic Uremic Syndrome in 2 Families from France | Zendy

Véronique Houdouin | Zendy; D. Catherine | Zendy; Pier Paolo Mariani | Zendy; N. Brahimi | Zendy; Chantal Loirat | Zendy; A Bourrillon | Zendy; Édouard Bingen | Zendy

Open Access

A Pediatric Cluster of Shigella dysenteriae Serotype 1 Diarrhea with Hemolytic Uremic Syndrome in 2 Families from France

Author(s) -

Véronique Houdouin,

D. Catherine,

Pier Paolo Mariani,

N. Brahimi,

Chantal Loirat,

A Bourrillon,

Édouard Bingen

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/383474

Subject(s) - shigella dysenteriae , medicine , serotype , diarrhea , shigella , ribotyping , dysentery , cluster (spacecraft) , pediatrics , microbiology and biotechnology , virology , salmonella , bacteria , biology , polymerase chain reaction , escherichia coli , pathology , computer science , gene , programming language , biochemistry , genetics

We report a cluster of pediatric diarrhea due to Shigella dysenteriae serotype 1 involving 11 children in France, including the index case, who had returned from Senegal. Child-to-child transmission was documented by ribotyping. Five children developed hemolytic uremic syndrome (HUS). On the basis of our findings, the choice of antimicrobial treatment for infections with S. dysenteriae serotype 1 should take into account widespread drug resistance and the risk of HUS.

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