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Community‐Onset Methicillin‐ResistantStaphylococcus aureusAssociated with Antibiotic Use and the Cytotoxin Panton‐Valentine Leukocidin during a Furunculosis Outbreak in Rural Alaska
Author(s) -
Henry C. Baggett,
Thomas W. Hennessy,
Karen Rudolph,
Dana Bruden,
Alisa Reasonover,
Alan J. Parkinson,
Rachel Sparks,
Rodney M. Donlan,
Patricia Martinez,
Kanokporn Mongkolrattanothai,
Jay C. Butler
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/383247
Subject(s) - panton–valentine leukocidin , outbreak , staphylococcus aureus , methicillin resistant staphylococcus aureus , leukocidin , pulsed field gel electrophoresis , microbiology and biotechnology , medicine , antibiotics , odds ratio , staphylococcal skin infections , staphylococcal infections , meticillin , skin infection , micrococcaceae , antibacterial agent , virology , biology , genotype , bacteria , biochemistry , gene , genetics
Community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) reports are increasing, and infections often involve soft tissue. During a CO-MRSA skin infection outbreak in Alaska, we assessed risk factors for disease and whether a virulence factor, Panton-Valentine leukocidin (PVL), could account for the high rates of MRSA skin infection in this region.

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