Age‐Associated Decline in Resistance toBabesia microtiIs Genetically Determined | Zendy

Edouard Vannier | Zendy; Ingo Borggraefe | Zendy; Samuel R. Telford | Zendy; Sanjay Me | Zendy; Timothy Brauns | Zendy; Andrew Spielman | Zendy; Jeffrey A. Gelfand | Zendy; Henry H. Wortis | Zendy

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Age‐Associated Decline in Resistance toBabesia microtiIs Genetically Determined

Author(s) -

Edouard Vannier,

Ingo Borggraefe,

Samuel R. Telford,

Sanjay Me,

Timothy Brauns,

Andrew Spielman,

Jeffrey A. Gelfand,

Henry H. Wortis

Publication year - 2004

Publication title -

the journal of infectious diseases

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/382965

Subject(s) - parasitemia , biology , immunity , immunology , acquired immune system , virology , immune system , allele , babesiosis , malaria , splenocyte , genetics , gene , plasmodium falciparum

Although infection by the protozoan Babesia microti is rarely symptomatic in immunocompetent young people, healthy individuals aged >50 years may experience life-threatening disease. To determine the basis for this age relationship, we developed a mouse model of babesiosis using a novel clinical isolate of B. microti.

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