Nutritionally Variant Streptococcal Infections at a University Hospital in Taiwan: Disease Emergence and High Prevalence of β‐Lactam and Macrolide Resistance
Author(s) -
ChungHsin Liao,
LeeJene Teng,
PoRen Hsueh,
YuChi Chen,
LiMin Huang,
ShanChwen Chang,
ShenWu Ho
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/381098
Subject(s) - medicine , cefotaxime , azithromycin , bacteremia , infective endocarditis , penicillin , endocarditis , antibiotics , microbiology and biotechnology , biology
From January 1993 to December 2002, 28 patients with nutritionally variant streptococci (NVS) infections were treated at a university hospital in Taiwan. Twelve (43%) of these patients had various underlying malignancies, and 7 (25%) had underlying valvular heart diseases. Nine patients (32%) had infective endocarditis, and 9 (32%) had primary bacteremia. The deaths of 7 patients (25%) were directly related to NVS infection. Among the 28 isolates recovered from these patients, 50% were not susceptible to penicillin, 33% were not susceptible to cefotaxime, and 93% were not susceptible to azithromycin.
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