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Schistosomiasis Does Not Contribute to Death or Recurrence of Nontyphoid Salmonella Bacteremia in Human Immunodeficiency Virus-Infected Malawian Adults
Author(s) -
Melita A. Gordon,
Eduard E. Zijlstra,
Cynthia W. A. Naus,
Leo G. Visser,
Malcolm E. Molyneux,
Lisette van Lieshout
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/379828
Subject(s) - bacteremia , medicine , coinfection , schistosomiasis , immunology , population , sida , virology , virus , viral disease , antibiotics , microbiology and biotechnology , biology , helminths , environmental health
Nontyphoid Salmonella (NTS) bacteremia has a very high mortality and recurrence rate among human immunodeficiency virus (HIV)-infected Malawian adults. Concurrent schistosomal infection might cause persistence of NTS infection and poor response to antibiotic therapy. Therefore, we tested serum samples for Schistosoma-specific circulating anodic antigen to diagnose coinfection with schistosomiasis among consecutive HIV-positive adults with NTS bacteremia. The results suggest that active schistosomiasis is not associated with adverse outcome of NTS bacteremia in this population, in contrast to other groups.

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