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Variation of Human Herpesvirus 7 Shedding in Saliva
Author(s) -
Masaru Ihira,
Tetsushi Yoshikawa,
Masahiro Ohashi,
Yoshihiko Enomono,
Shiho Akimoto,
Sadao Suga,
Hiroh Saji,
Yukihiro Nishiyama,
Yoshizo Asano
Publication year - 2003
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/379040
Subject(s) - saliva , viral shedding , titer , virus , virology , human herpesvirus , biology , antibody , human herpesvirus 6 , immunology , herpesviridae , viral disease , biochemistry
Sequential analysis of human herpesvirus 7 (HHV-7) shedding in saliva obtained from healthy adults was performed for 6 months; virus was isolated in 92 (34.1%) of the 270 saliva samples obtained. Frequency of HHV-7 shedding in serially obtained saliva samples varied among subjects. Associations between frequency of HHV-7 shedding and age, sex, and virus antibody titer were analyzed, and, although sex was not associated with frequency of shedding, young age (P=.031) and low antibody titer (P=.006) were correlated with frequent viral shedding (5 or 6 times/6 months).

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