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High Incidence of Pertussis among Hajj Pilgrims
Author(s) -
Annelies WilderSmith,
Arul Earnest,
Sundari Ravindran,
Nicholas I. Paton
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/378748
Subject(s) - hajj , medicine , whooping cough , incidence (geometry) , herd immunity , pertussis vaccine , immunity , immunology , bordetella pertussis , pertussis toxin , pediatrics , antibody , vaccination , immunization , immune system , philosophy , physics , theology , islam , optics , genetics , receptor , g protein , biology , bacteria
Prolonged cough occurs in a large proportion of the 2 million pilgrims who participate in the annual Hajj in Saudi Arabia. In a prospective seroepidemiological study to determine the incidence of pertussis among 358 adult pilgrims, 5 (1.4%) were found to have acquired pertussis (defined as prolonged cough and a >4-fold increase in the level of immunoglobulin G to whole-cell pertussis antigen). Of the 40 pilgrims who had no pre-Hajj immunity to pertussis, 3 (7.5%) acquired pertussis. Administration of acellular pertussis vaccine to pilgrims before the Hajj should be considered to address this problem.

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