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Common Adverse Events Associated with the Use of Ribavirin for Severe Acute Respiratory Syndrome in Canada
Author(s) -
Simon R. Knowles,
Elizabeth J. Phillips,
Linda Dresser,
Larissa Matukas
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/378304
Subject(s) - ribavirin , medicine , adverse effect , respiratory system , intensive care medicine , virology , virus , hepatitis c virus
Although information on efficacy and adverse drug reactions is lacking, ribavirin has been used empirically for the treatment of severe acute respiratory syndrome (SARS). We report common adverse events in 110 patients with suspected or probable SARS who were treated with ribavirin. Sixty-one percent of the patients had evidence of hemolytic anemia, and hypocalcemia and hypomagnesmia were reported in 58% and 46% of patients, respectively.

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