Bone Marrow Failure Associated with Herpesvirus 8 Infection in a Patient Undergoing Autologous Peripheral Blood Stem Cell Transplantation
Author(s) -
Maria Cuzzola,
Giuseppe Irrera,
O. Iacopino,
Alfredo Cuzzocrea,
Giovanni Messina,
Giuseppe Console,
Pasquale Iacopino,
Fortunato Morabito
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/377268
Subject(s) - medicine , bone marrow , lymphoma , human herpesvirus 6 , stem cell , transplantation , herpesviridae , immunology , surgery , viral disease , virus , biology , genetics
We describe a fatal case of human herpesvirus 8-associated bone marrow failure in a patient who had received intense treatment for Hodgkin lymphoma and was undergoing bone marrow transplantation. Bone marrow failure was resistant to antiviral treatment and a second infusion of autologous stem cells. Human herpesvirus 8 infection continues to be a major concern in transplant recipients in critical condition.
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