Fatal Human Rabies Caused by European Bat Lyssavirus Type 2a Infection in Scotland
Author(s) -
Dilip Nathwani,
P. G. McIntyre,
Kathleen M. White,
A. J. Shearer,
Nick J. Reynolds,
David Walker,
G. Orange,
A. R. Fooks
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/376641
Subject(s) - rabies , lyssavirus , medicine , virology , rabies virus , paralysis , flaccid paralysis , encephalitis , insectivore , immunization , immunology , rhabdoviridae , virus , biology , antibody , psychiatry , ecology , predation
We wish to report the first recorded case of indigenous human rabies caused by a bat bite in the United Kingdom in 100 years. This instructive case report highlights a number of key lessons: first, bites from insectivorous bats indiginous to the United Kingdom can cause rabies in humans; second, rabies immunization is essential for bat-handlers, and postexposure treatment for rabies is essential for patients bitten by bats; third, patients able to give a history who present with acute flaccid paralysis and/or presumptive viral encephalitis should be asked if they have been bitten by bats, irrespective of travel history, or this history should be obtained from family or friends; fourth, antemortem diagnosis of bat rabies (EBLV type 2a infection) in humans is possible using RT-PCR.
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