Isolated Pulmonary Mycobacterium avium Complex Infection in Patients with Human Immunodeficiency Virus Infection: Case Reports and Literature Review
Author(s) -
C Salama,
Maurice Policar,
M. Venkataraman
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/375895
Subject(s) - medicine , immune system , mycobacterium avium complex , immune reconstitution inflammatory syndrome , bronchoscopy , immunopathology , mycobacterium avium intracellulare infection , immunology , granuloma , human immunodeficiency virus (hiv) , biopsy , aids related opportunistic infections , opportunistic infection , sida , viral disease , mycobacterium , pathology , tuberculosis , antiretroviral therapy , viral load
We report 4 cases of isolated pulmonary Mycobacterium avium complex (MAC) infection and review the 20 previously reported cases in the human immunodeficiency virus literature. All 4 patients had acquired immune deficiency syndrome, and 3 were believed to have had an immune reconstitution syndrome as a cause of MAC infection. Two patients underwent bronchoscopy with biopsy, revealing endobronchial lesions and granuloma formation, and all 4 patients responded well to MAC therapy.
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