Factors Associated with Oropharyngeal Human Immunodeficiency Virus Shedding | Zendy

Richard A. Zuckerman | Zendy; William L. H. Whittington | Zendy; Connie Celum | Zendy; Tarquin Collis | Zendy; Aldo Lucchetti | Zendy; Jorge L. Sánchez | Zendy; James P. Hughes | Zendy; José L. Sánchez | Zendy; Robert W. Coombs | Zendy

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Factors Associated with Oropharyngeal Human Immunodeficiency Virus Shedding

Author(s) -

Richard A. Zuckerman,

William L. H. Whittington,

Connie Celum,

Tarquin Collis,

Aldo Lucchetti,

Jorge L. Sánchez,

James P. Hughes,

José L. Sánchez,

Robert W. Coombs

Publication year - 2003

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/375741

Subject(s) - saliva , viral shedding , medicine , human immunodeficiency virus (hiv) , virology , multivariate analysis , sida , transmission (telecommunications) , lentivirus , viral disease , virus , immunology , electrical engineering , engineering

Orogenital transmission of human immunodeficiency virus (HIV) is considered to be inefficient, and infectious HIV is rarely detected in saliva. To evaluate the posterior oropharynx as a source of HIV shedding, we studied 64 HIV-infected men who have sex with men in Seattle, Washington, and Lima, Peru. In multivariate analysis, receipt of antiretroviral therapy, higher CD4 cell count, and history of tonsillectomy were predictors of lower pharyngeal HIV RNA levels.

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