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We report the case of a 52-year-old immunocompetent man with varicella-zoster virus large-vessel vasculopathy and multiple bilateral cerebral infarcts who had no history of skin involvement. Etiologic diagnosis was made by isolation of varicella-zoster virus from a cerebrospinal fluid specimen. The patient had marked improvement in mental status after acyclovir therapy was initiated.

Multiple Cerebral Infarcts Due to Varicella-Zoster Virus Large-Vessel Vasculopathy in an Immunocompetent Adult without Skin Involvement