Opportunities and Options for Treatment Research in Resource‐Constrained Settings | Zendy

Paul A. Volberding | Zendy

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Opportunities and Options for Treatment Research in Resource‐Constrained Settings

Author(s) -

Paul A. Volberding

Publication year - 2003

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/375366

Subject(s) - medicine , observational study , clinical trial , resource (disambiguation) , clinical research , intensive care medicine , human immunodeficiency virus (hiv) , research design , clinical study design , cohort study , family medicine , pathology , computer science , computer network , social science , sociology

HIV clinical research faces limitations even in research-rich settings. Even though important questions remain unanswered, clinical trials will probably never be conducted that address, prospectively, when treatment is optimally indicated, for example. In resource-constrained settings, large, prospective clinical trials are also unlikely. On the other hand, ones with a more observational design or that compare cohort experiences may well be feasible and able to provide information important in those settings, as well as in regions with abundant financial resources.

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