The Efficacy of Oral Ribavirin in the Treatment of Crimean-Congo Hemorrhagic Fever in Iran | Zendy

Masoud Mardani | Zendy; Maryam Koushkie Jahromi | Zendy; Kourosh Holakoie naieni | Zendy; Mohammad Zeinali | Zendy

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The Efficacy of Oral Ribavirin in the Treatment of Crimean-Congo Hemorrhagic Fever in Iran

Author(s) -

Masoud Mardani,

Maryam Koushkie Jahromi,

Kourosh Holakoie naieni,

Mohammad Zeinali

Publication year - 2003

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/375058

Subject(s) - ribavirin , crimean–congo hemorrhagic fever , medicine , virology , virus , disease , hepatitis c virus

We compared the mortality rate among patients suspected of having Crimean-Congo hemorrhagic fever (CCHF) who received treatment with oral ribavirin and those who did not. Ninety-seven (69.8%) of 139 treated patients suspected of having CCHF survived, and 61 (88.9%) of 69 treated patients with confirmed CCHF survived. The efficacy of oral ribavirin was 80% among patients with confirmed CCHF and 34% among patients suspected of having CCHF. Considering the limitations of observational studies, we conclude that oral ribavirin is an effective treatment for the hemorrhagic form of CCHF.

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