Smallpox Vaccination and the Patient with an Organ Transplant
Author(s) -
Lesia K. Dropulic,
Robert H. Rubin,
John G. Bartlett
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/374716
Subject(s) - medicine , vaccination , smallpox , immunology , organ transplantation , immunity , intensive care medicine , population , disease , smallpox vaccine , vaccinia , transplantation , immune system , surgery , environmental health , recombinant dna , biochemistry , chemistry , gene
Organ transplant recipients are vulnerable to a variety of infections because of the immunosuppressed state required to prevent organ rejection. We review the recommendations of the Centers for Disease Control and Prevention (Atlanta, Georgia) for smallpox vaccination and the possible complications of vaccination in the population with organ transplants. The risk of these complications is presumably dependent on the extent of deficient cell-mediated immunity.
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