Vascular Thrombosis and Acute Cytomegalovirus Infection in Immunocompetent Patients: Report of 2 Cases and Literature Review | Zendy

P. Abgueguen | Zendy; V. Delbos | Zendy; J.M. Chennebault | Zendy; Christopher Payan | Zendy; É. Pichard | Zendy

Open Access

Vascular Thrombosis and Acute Cytomegalovirus Infection in Immunocompetent Patients: Report of 2 Cases and Literature Review

Author(s) -

P. Abgueguen,

V. Delbos,

J.M. Chennebault,

Christopher Payan,

É. Pichard

Publication year - 2003

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/374664

Subject(s) - medicine , thrombosis , cytomegalovirus , asymptomatic , pulmonary embolism , myocarditis , pneumonia , immunology , venous thrombosis , viral disease , herpesviridae , virus

Acute cytomegalovirus (CMV) infection in immunocompetent patients is common worldwide, with seroprevalence rates of 40%-100%, depending on the country, socioeconomic conditions, and the patient's age. Infection is most often asymptomatic, but acute cytomegalovirus infection is occasionally revealed by prolonged fever, cervical lymphadenitis, and arthralgia, and it is more rarely revealed by pneumonia, myocarditis, pericarditis, colitis, and hemolytic anemia. Here, we report 2 cases of acute CMV infection in nonimmunocompromised adults that were complicated by venous thrombosis with pulmonary embolism. We also review previously reported cases of vascular thrombosis and discuss the propensity of CMV to induce vascular damage with associated thrombosis.

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