Decrease in Human Immunodeficiency Virus Type 1 Load during Acute Dengue Fever | Zendy

George Watt | Zendy; Pacharee Kantipong | Zendy; Krisada Jongsakul | Zendy

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Decrease in Human Immunodeficiency Virus Type 1 Load during Acute Dengue Fever

Author(s) -

George Watt,

Pacharee Kantipong,

Krisada Jongsakul

Publication year - 2003

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/374600

Subject(s) - dengue fever , medicine , virology , dengue virus , measles , scrub typhus , infectivity , immunology , peripheral blood mononuclear cell , viral load , human immunodeficiency virus (hiv) , viral disease , virus , biology , vaccination , in vitro , biochemistry

Rather than the expected increase in human immunodeficiency virus type 1 (HIV-1) load, there was transient suppression of HIV-1 replication during acute dengue infection in a 29-year-old Thai woman. Acute-phase (but not convalescent-phase) serum samples obtained from an HIV-1-uninfected patient with dengue fever reduced HIV-1 infectivity, as determined by a peripheral blood mononuclear cell assay, suggesting the possibility that HIV-1 replication is suppressed during acute dengue fever, as occurs during some cases of scrub typhus infection and measles.

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