Knowledge of Antiretroviral Regimen Dosing and Adherence: A Longitudinal Study
Author(s) -
Loren G. Miller,
Honghu Liu,
Ron D. Hays,
Carol E. Golin,
Zhishen Ye,
Christopher Beck,
Andrew H. Kaplan,
Neil S. Wenger
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/367857
Subject(s) - regimen , dosing , medicine , cohort , multivariate analysis , human immunodeficiency virus (hiv) , immunology
In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.
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