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A critically ill patient with septicemic plague and peripheral gangrene was treated successfully with ciprofloxacin. There are no previous reports of plague being successfully treated with ciprofloxacin. Peripheral gangrene of this patient's feet was managed with use of sympathetic blockade; the patient's toes appear to have been saved by this approach.

A Case of Plague Successfully Treated with Ciprofloxacin and Sympathetic Blockade for Treatment of Gangrene