Hepatitis C Virus Seroconversion among Young Injection Drug Users: Relationships and Risks | Zendy

Judith A. Hahn | Zendy; Kimberly Page | Zendy; Paula J. Lum | Zendy; Philippe Bourgois | Zendy; Ellen Stein | Zendy; Jennifer L. Evans | Zendy; Michael P. Busch | Zendy; Leslie H. Tobler | Zendy; Bruce H. Phelps | Zendy; Andrew R. Moss | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Hepatitis C Virus Seroconversion among Young Injection Drug Users: Relationships and Risks

Author(s) -

Judith A. Hahn,

Kimberly Page,

Paula J. Lum,

Philippe Bourgois,

Ellen Stein,

Jennifer L. Evans,

Michael P. Busch,

Leslie H. Tobler,

Bruce H. Phelps,

Andrew R. Moss

Publication year - 2002

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/345554

Subject(s) - seroconversion , medicine , needle sharing , incidence (geometry) , hepatitis c , hepatitis c virus , cohort , transmission (telecommunications) , sexual transmission , cohort study , psychological intervention , prospective cohort study , immunology , confidence interval , antibody , virus , human immunodeficiency virus (hiv) , condom , psychiatry , physics , electrical engineering , microbicide , syphilis , optics , engineering

The present study examined reasons for the high incidence of hepatitis C virus (HCV) infection among young injection drug users (IDUs). IDUs <30 years old who tested negative for HCV antibody were enrolled in a prospective cohort. Risk factors for seroconversion were examined using time-dependent regression analyses: 48 of 195 IDUs seroconverted to HCV, for an incidence rate of 25.1/100 person-years (95% confidence interval, 18.7-32.9/100 person-years). Independent risk factors included sharing needles with an HCV-infected sex partner (borderline statistical significance, P=.11) or a person who was not a sex partner, sharing nonsterile drug-preparation equipment, pooling money with another IDU to buy drugs, and exchanging sex for money. Ubiquitous behaviors among young IDUs, such as the forming of injecting or sexual partnerships and consequent sharing of needles and drug preparation equipment, are risk factors for HCV. Interventions to reduce HCV transmission must recognize the importance of relationships on injecting risk.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research