Recurrent Kawasaki Disease–like Syndrome in a Patient with Acquired Immunodeficiency Syndrome
Author(s) -
Jennifer Blanchard,
Henry C. Powell,
William R. Freeman,
Scott Letendre,
Daniel G. Blanchard,
Chisato Shimizu,
Jane C. Burns
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/345465
Subject(s) - medicine , kawasaki disease , vasculitis , immunopathology , vascular disease , immunology , viral disease , antibody , disease , systemic disease , immunodeficiency , pathology , virus , immune system , artery
A review of Kawasaki disease (KD)-like syndromes (KDLS) in patients with human immunodeficiency virus (HIV) raised the question whether vasculitis in children and KDLS in immunocompromised adults might be etiologically related. We describe a 42-year-old white man with AIDS and Kaposi sarcoma who presented with KDLS, which was diagnosed on the basis of clinical criteria for KD. Analysis of a conjunctival tissue sample revealed endothelial cell damage with fibrin deposition and infiltration of immunoglobulin A-secreting plasma cells.
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