Postmalaria Neurological Syndrome: Two Cases from The Gambia
Author(s) -
Stephen D Lawn,
Katie L. Flanagan,
Stephen G. Wright,
Tom Doherty,
Peter GodfreyFaussett
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/344774
Subject(s) - medicine , convalescence , myoclonus , confusion , malaria , plasmodium falciparum , neurological deficit , cerebrospinal fluid , neurological disorder , pediatrics , surgery , anesthesia , central nervous system disease , pathology , psychology , psychoanalysis
We describe 2 patients with severe Plasmodium falciparum malaria whose convalescence was complicated by fever, with acute confusion and acalculia in one patient and a triad of myoclonus, tremor, and dysphasia in the other. Inflammatory changes were found in cerebrospinal fluid samples. Postmalaria neurological syndrome was diagnosed in each patient, and a therapeutic response to oral corticosteroids was seen in the second patient.
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