High Rate of Monoclonal Gammopathy among Immunocompetent Subjects with Primary Cytomegalovirus Infection | Zendy

Suvi Bühler | Zendy; Kalevi Laitinen | Zendy; Harry Holthöfer | Zendy; Asko Järvinen | Zendy; KnutOlof Schauman | Zendy; Klaus Hedman | Zendy

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High Rate of Monoclonal Gammopathy among Immunocompetent Subjects with Primary Cytomegalovirus Infection

Author(s) -

Suvi Bühler,

Kalevi Laitinen,

Harry Holthöfer,

Asko Järvinen,

KnutOlof Schauman,

Klaus Hedman

Publication year - 2002

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/344465

Subject(s) - medicine , cytomegalovirus , paraproteins , cytomegalovirus infection , betaherpesvirinae , immunology , malignancy , herpesviridae , immunocompetence , epstein–barr virus infection , lymphoproliferative disorders , human cytomegalovirus , epstein–barr virus , monoclonal , virology , virus , viral disease , lymphoma , pathology , immune system , monoclonal antibody , antibody

Serum samples from immunocompetent adults with primary cytomegalovirus (CMV) or Epstein-Barr virus (EBV) infection and from solid-organ or bone marrow transplant recipients with primary CMV infection were examined for paraproteins. Several immunocompetent patients with CMV infection but none with EBV infection presented with an M component, which implies that the M component connects CMV infection to a risk of B cell malignancy.

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