Viable but NonculturableSalmonellaSpecies Recovery and Systemic Infection in Morphine‐Treated Mice | Zendy

Hiroshi Asakura | Zendy; Masahisa Watarai | Zendy; Toshikazu Shirahata | Zendy; Souichi Makino | Zendy

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Viable but NonculturableSalmonellaSpecies Recovery and Systemic Infection in Morphine‐Treated Mice

Author(s) -

Hiroshi Asakura,

Masahisa Watarai,

Toshikazu Shirahata,

Souichi Makino

Publication year - 2002

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/344353

Subject(s) - viable but nonculturable , salmonella enterica , microbiology and biotechnology , salmonella , bacteremia , biology , bioassay , in vivo , serotype , morphine , salmonella infection , virology , bacteria , pharmacology , antibiotics , genetics

In vivo recovery and pathogenicity of Salmonella enterica serovar Oranienburg that became viable but nonculturable (VNC) in food were examined. VNC cells were completely eliminated in normal mice but caused systemic bacteremia and were subsequently lethal to morphine-treated mice. Therefore, morphine-treated mice might be a useful bioassay for VNC Salmonella species in implicated food items.

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