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We describe the annual incidence of primary bloodstream infection (BSI) associated with Candida albicans and common non-albicans species of Candida among patients in intensive care units that participated in the National Nosocomial Infections Surveillance system from 1 January 1989 through 31 December 1999. During the study period, there was a significant decrease in the incidence of C. albicans BSI (P&lt;.001) and a significant increase in the incidence of Candida glabrata BSI (P=.05).

Secular Trend of Hospital‐Acquired Candidemia among Intensive Care Unit Patients in the United States during 1989–1999