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The Menstrual Cycle Does Not Affect Human Immunodeficiency Virus Type 1 Levels in Vaginal Secretions
Author(s) -
Patricia Reichelderfer,
Andrea Kovács,
David J. Wright,
Alan Landay,
Susan CuUvin,
David Burns,
Jonathan Cohn,
Robert W. Coombs
Publication year - 2002
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/342051
Subject(s) - menstrual cycle , human immunodeficiency virus (hiv) , affect (linguistics) , vaginal secretion , medicine , physiology , immunology , biology , hormone , gynecology , psychology , communication
To determine whether the menstrual cycle affects human immunodeficiency virus (HIV) type 1 levels in vaginal secretions, vaginal lavage samples were collected at 7, 14, and 21 days after initiation of menses, to compare virus levels during the follicular, ovulatory, and luteal phases. During 33 menstrual cycles in 25 women, HIV-1 RNA levels in vaginal secretions ranged from .05). These results suggest that hormonal changes during the menstrual cycle do not have a significant effect on HIV-1 RNA levels in vaginal secretions.

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