Role of Bacteriophage MAV1 as a Mycoplasmal Virulence Factor for the Development of Arthritis in Mice and Rats | Zendy

Anh-Hue Thi Tu | Zendy; J. Russell Lindsey | Zendy; Trenton R. Schoeb | Zendy; Ada Elgavish | Zendy; Huilan Yu | Zendy; Kevin Dybvig | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Role of Bacteriophage MAV1 as a Mycoplasmal Virulence Factor for the Development of Arthritis in Mice and Rats

Author(s) -

Anh-Hue Thi Tu,

J. Russell Lindsey,

Trenton R. Schoeb,

Ada Elgavish,

Huilan Yu,

Kevin Dybvig

Publication year - 2002

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/341458

Subject(s) - virulence , bacteriophage , virulence factor , arthritis , microbiology and biotechnology , virology , biology , immunology , medicine , genetics , escherichia coli , gene

The lysogenic bacteriophage MAV1 has been shown to be a virulence factor for the development of arthritis in rats infected with Mycoplasma arthritidis. In the present study, arthritis was evaluated by histopathologic examination to demonstrate that MAV1 is a virulence factor not only in the rat but also in the mouse. Specifically, the MAV1 lysogen 158L3-1 was more virulent than the nonlysogen strain 158 in DBA/2NCr, C3H/HeNCr, C3H/HeJ, and C3Smn.CB17-Prkdc(scid)/J mice, as well as in LEW rats.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research