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Virus Load during Primary Human Immunodeficiency Virus (HIV) Type 1 Infection Is Related to the Severity of Acute HIV Illness in Kenyan Women
Author(s) -
Ludo Lavreys,
Jared M. Baeten,
Julie Overbaugh,
Dana Panteleeff,
Bhavna Chohan,
Barbra A. Richardson,
Kishorchandra Mandaliya,
Jeckoniah NdinyaAchola,
Joan K. Kreiss
Publication year - 2002
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/340862
Subject(s) - medicine , sore throat , seroconversion , myalgia , virus , immunology , viral load , rash , virology , viral disease
We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes in Mombasa, Kenya. Fever, vomiting, headache, fatigue, arthralgia, myalgia, sore throat, skin rash, or being too sick to work were each associated with significantly higher virus loads before HIV-1 seroconversion, and each additional symptom or sign was associated with an increase in virus load of 0.4 log(10) copies/mL.

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