Assessing Eosinophil Count as a Marker of Immune Activation among Human Immunodeficiency Virus–Infected Persons in Sub‐Saharan Africa
Author(s) -
Terence Chorba,
John N. Nkengasong,
Thierry H. Roels,
B. Monga,
C Maurice,
M. Maran,
Gaston Djomand
Publication year - 2002
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/339940
Subject(s) - eosinophil , immunology , medicine , virus , human immunodeficiency virus (hiv) , immune system , immunopathology , virology , surrogate endpoint , viral load , asthma
In 611 human immunodeficiency virus-infected persons who had not yet begun to receive antiretroviral therapy, we evaluated the linear association between absolute eosinophil count (as a surrogate for immune response to helminthic infection) and CD4+ T cell count, and between absolute eosinophil count and log virus load. Overall, no significant correlations were observed between eosinophil count and CD4+ T cell count, or between eosinophil count and log virus load.
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