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Evidence for Probable Sexual Transmission of the Hepatitis G Virus
Author(s) -
Sharon E. Frey,
Sharon M. Homan,
Marcia L. Sokol-Anderson,
Margarita Torralba Cayco,
Prospero Cortorreal,
C E Musial,
Adrian M. Di Bisceglie
Publication year - 2002
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/339206
Subject(s) - medicine , sexual transmission , virology , transmission (telecommunications) , epidemiology , hepatitis c virus , virus , hepatitis , viral disease , gb virus c , polymerase chain reaction , flaviviridae , sexually transmitted disease , immunology , syphilis , biology , biochemistry , microbicide , human immunodeficiency virus (hiv) , electrical engineering , gene , engineering
A cross-sectional epidemiology study evaluated the role of sexual activity and sexually transmitted diseases (STDs) in the transmission of hepatitis G virus (HGV/GBV-C) and other hepatitis virus infections in 944 subjects. There was a statistically significant higher prevalence of HGV/GBV-C, hepatitis B virus, and hepatitis C virus exposure in the STD clinic group (i.e., subjects who were currently seeking treatment for an STD) compared with the group who never had received treatment for an STD. In a comparison of the subjects with an STD versus those without an STD, the prevalence of HGV/GBV-C was 11.3% versus 4.9%, on the basis of polymerase chain reaction (PCR) results alone, and 36.6% versus 8.8%, when results of PCR and enzyme-linked immunosorbent assay were combined. Sexual activity and, possibly, the presence of an STD increases the risk of HGB/GBV-C transmission.

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