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Intestinal Microsporidiosis Due toEnterocytozoon bieneusiin Elderly Human Immunodeficiency Virus–Negative Patients from Vigo, Spain
Author(s) -
B. Lores,
I. López-Miragaya,
Cristina Arias,
Soledad Fenoy,
Júlio Augusto do Prado Torres,
C. del Águila
Publication year - 2002
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/339205
Subject(s) - microsporidiosis , enterocytozoon bieneusi , diarrhea , medicine , virology , chronic diarrhea , opportunistic infection , aids related opportunistic infections , immunology , microsporidia , sida , virus , gastroenterology , viral disease , microbiology and biotechnology , biology , protozoal disease , malaria , spore
We report what is, to our knowledge, the first study in which microsporidial infection was detected in elderly human immunodeficiency virus (HIV)--negative patients. Of the 60 elderly patients studied, 47 had diarrhea. Intestinal microsporidiosis due to Enterocytozoon bieneusi was diagnosed in 8 patients (17.02%) by use of Weber's chromotrope-based stain and polymerase chain reaction with species-specific primers. The mean age of these 8 patients was 75 years; 7 had chronic diarrhea and 1 had nonchronic diarrhea. Six of the patients with chronic diarrhea had no other pathogens isolated. In our opinion, elderly patients, because of their special immunological characteristics, should be considered a group at risk for the acquisition of intestinal microsporidiosis.

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