Resuppression of Virus Load after Interruption in Treatment with Nevirapine and 2 Nucleoside Reverse-Transcriptase Inhibitors | Zendy

Joseph L Yozviak | Zendy; R. Doerfler | Zendy; William C. Woodward | Zendy

Open Access

Resuppression of Virus Load after Interruption in Treatment with Nevirapine and 2 Nucleoside Reverse-Transcriptase Inhibitors

Author(s) -

Joseph L Yozviak,

R. Doerfler,

William C. Woodward

Publication year - 2002

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/338726

Subject(s) - nevirapine , medicine , reverse transcriptase , virology , nucleoside reverse transcriptase inhibitor , reverse transcriptase inhibitor , nucleoside analogue , didanosine , nucleoside , human immunodeficiency virus (hiv) , virus , viral load , antiretroviral therapy , rna , biology , genetics , gene

This retrospective chart review evaluated the effectiveness of reinitiation of treatment with nevirapine and dual nucleoside-analogue reverse-transcriptase inhibitors (NRTIs) after an interruption in antiretroviral therapy in 135 patients with human immunodeficiency virus type 1 RNA levels of <400 copies/mL who were receiving the same regimen. Reinitiation of a nevirapine regimen resulted in resuppression of virus load to <400 copies/mL in most patients who adhered to the regimen. Direct interruption of a non-NRTI regimen could lead to easier and more efficient structured protocols for treatment interruption.

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