Discontinuation of Secondary Prophylaxis in Patients with Cytomegalovirus Retinitis Who Have Responded to Highly Active Antiretroviral Therapy | Zendy

Juan Berenguer | Zendy; J.J. González | Zendy; Federico Pulido | Zendy; B. Padilla | Zendy; José L. Casado | Zendy; Rafael Rubio | Zendy; José Ramón Arribas | Zendy

Open Access

Discontinuation of Secondary Prophylaxis in Patients with Cytomegalovirus Retinitis Who Have Responded to Highly Active Antiretroviral Therapy

Author(s) -

Juan Berenguer,

J.J. González,

Federico Pulido,

B. Padilla,

José L. Casado,

Rafael Rubio,

José Ramón Arribas

Publication year - 2002

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/338401

Subject(s) - discontinuation , medicine , retinitis , cytomegalovirus retinitis , cytomegalovirus , antiretroviral therapy , opportunistic infection , secondary prophylaxis , sida , human immunodeficiency virus (hiv) , pediatrics , immunology , viral disease , herpesviridae , human cytomegalovirus , viral load , virus

We performed a prospective study of discontinuation of secondary prophylaxis against cytomegalovirus (CMV) in 36 patients with acquired immunodeficiency syndrome and quiescent CMV retinitis after successful treatment with highly active antiretroviral therapy (HAART). No reactivation or progression of retinitis was observed in 35 patients with persistent response to HAART, findings that support the discontinuation of secondary prophylaxis against CMV retinitis in such patients.

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