Profound T‐Lymphocytopenia and Cryptococcemia in a Human Immunodeficiency Virus–Seronegative Patient with Disseminated Tuberculosis | Zendy

Gerasimos J. Zaharatos | Zendy; Marcel A. Behr | Zendy; Michael Libman | Zendy

Open Access

Profound T‐Lymphocytopenia and Cryptococcemia in a Human Immunodeficiency Virus–Seronegative Patient with Disseminated Tuberculosis

Author(s) -

Gerasimos J. Zaharatos,

Marcel A. Behr,

Michael Libman

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/324086

Subject(s) - lymphocytopenia , medicine , tuberculosis , pneumonia , immunology , cachexia , disease , immunodeficiency , immunopathology , virology , pathology , immune system , lymphocyte , cancer

A 47-year-old human immunodeficiency virus-seronegative West African man who presented in extremis with cachexia, lymphadenopathy, multiple organ dysfunction, and marked T-lymphocytopenia received the diagnosis of disseminated tuberculosis, cryptococcal pneumonia, and cryptococcemia. His subsequent course and our review of the literature suggest that the profound T-lymphocytopenia and ensuing cryptococcal disease were likely attributable to disseminated tuberculosis.

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