Lack of Seroconversion in a Health Care Worker after Polymerase Chain Reaction–Documented Acute Hepatitis C Resulting from a Needlestick Injury | Zendy

Patrice Morand | Zendy; N. Dutertre | Zendy; H Minazzi | Zendy; Jean Burnichon | Zendy; Martine Pernollet | Zendy; Maryline Baud | Zendy; JeanPierre Zarski | Zendy; JeanMarie Seigneurin | Zendy

Open Access

Lack of Seroconversion in a Health Care Worker after Polymerase Chain Reaction–Documented Acute Hepatitis C Resulting from a Needlestick Injury

Author(s) -

Patrice Morand,

N. Dutertre,

H Minazzi,

Jean Burnichon,

Martine Pernollet,

Maryline Baud,

JeanPierre Zarski,

JeanMarie Seigneurin

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/322619

Subject(s) - medicine , seroconversion , hepatitis c virus , hepatitis c , serology , needlestick injury , ribavirin , virology , immunology , viral disease , antibody , human immunodeficiency virus (hiv) , virus

We present a case of documented acute hepatitis C that occurred in a health care worker who sustained a needlestick injury while caring for an individual who was infected with both hepatitis C virus (HCV) and human immunodeficiency virus (HIV). According to the findings of third-generation serological assays performed during a follow-up of >1 year, the health care worker, who was treated with interferon-alpha (during weeks 2-6) and ribavirin (during weeks 5-9), did not develop antibodies against HCV, in spite of documentation of an HCV-specific T cell response.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research