Two Episodes of Leukoencephalitis Associated with Recombinant Hepatitis B Vaccination in a Single Patient | Zendy

Demetrios Konstantinou | Zendy; C. Paschalis | Zendy; Theodoros Maraziotis | Zendy; Panagiotis Dimopoulos | Zendy; Harry P. Bassaris | Zendy; Athanasios Skoutelis | Zendy

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Two Episodes of Leukoencephalitis Associated with Recombinant Hepatitis B Vaccination in a Single Patient

Author(s) -

Demetrios Konstantinou,

C. Paschalis,

Theodoros Maraziotis,

Panagiotis Dimopoulos,

Harry P. Bassaris,

Athanasios Skoutelis

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/322617

Subject(s) - medicine , vaccination , virology , immunology , recombinant dna , hepatitis b , hepatitis , viral disease , virus , biochemistry , chemistry , gene

Cases of central nervous system demyelination have been reported after recombinant hepatitis B vaccination, but no causal link has been clearly demonstrated. We present the first case report involving the occurrence of 2 episodes of leukoencephalitis in a previously healthy patient after vaccination and rechallenge with hepatitis B vaccine.

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