Investigation of Primary Human Immunodeficiency Virus Infection in Patients Who Test Positive for Heterophile Antibody | Zendy

Rochelle P. Walensky | Zendy; Eric Rosenberg | Zendy; Mary Jane Ferraro | Zendy; Elena Losina | Zendy; Bruce D. Walker | Zendy; Kenneth A. Freedberg | Zendy

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Investigation of Primary Human Immunodeficiency Virus Infection in Patients Who Test Positive for Heterophile Antibody

Author(s) -

Rochelle P. Walensky,

Eric Rosenberg,

Mary Jane Ferraro,

Elena Losina,

Bruce D. Walker,

Kenneth A. Freedberg

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/321903

Subject(s) - heterophile , medicine , human immunodeficiency virus (hiv) , antibody , immunology , virology

In light of a recent report of 3 false-positive results of Epstein-Barr virus heterophile tests caused by HIV infection, we sought to assess the frequency of this occurrence. One hundred thirty-two positive heterophile antibody-tested serum samples were obtained from 2 tertiary care facilities in Boston to assess for HIV, and all tested negative for HIV plasma RNA. This study shows that false-positive results of heterophile tests are not frequently associated with primary HIV infection.

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