Epidemic Typhus Meningitis in the Southwestern United States | Zendy

Robert F. Massung | Zendy; L. E. Davis | Zendy; Kimetha Slater | Zendy; Don B. McKechnie | Zendy; M. Puerzer | Zendy

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Epidemic Typhus Meningitis in the Southwestern United States

Author(s) -

Robert F. Massung,

L. E. Davis,

Kimetha Slater,

Don B. McKechnie,

M. Puerzer

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/319351

Subject(s) - murine typhus , typhus , rickettsia typhi , rickettsia prowazekii , medicine , virology , meningitis , rickettsiosis , polymerase chain reaction , rickettsia , virus , pediatrics , biology , gene , biochemistry

A patient residing in New Mexico had murine typhus diagnosed. A novel molecular assay was performed at the Centers for Disease Control and Prevention, and Rickettsia prowazekii, the agent of epidemic typhus, was found, rather than R. typhi. To our knowledge, this is the first reported case of epidemic typhus confirmed by means of polymerase chain reaction--based testing of cerebrospinal fluid, and it introduces a novel assay for the molecular diagnosis of both epidemic and murine typhus.

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