Open AccessInvasive Group B Streptococcal Disease in Maryland Nursing Home Residents
Author(s) -
Kelly Henning,
Elvira L. Hall,
Diane M. Dwyer,
Lillian Billmann,
Anne Schuchat,
Judith A. Johnson,
Lee H. Harrison
Publication year - 2001
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/319278
Subject(s) - incidence (geometry) , medicine , subtyping , group b , serotype , streptococcus agalactiae , streptococcus , population , transmission (telecommunications) , nursing homes , group a , pediatrics , nursing , immunology , environmental health , biology , physics , electrical engineering , computer science , bacteria , optics , genetics , programming language , engineering
Between 1991 and 1995, among 999 nonpregnant adult Maryland residents with group B Streptococcus (GBS) isolated from a normally sterile site, 84 resided in nursing homes (NHs). The age-adjusted annual incidence of GBS infection (per 100,000 population) among those > or = 65 years old was 72.3 for NH residents and 17.5 for community residents (relative risk, 4.1; P < 0.001). Thirty-four case patients resided in 11 NHs with > or = 2 cases; 1 NH had 8 case patients within 22 months. Six of 8 case patients from 3 NHs had serotype V GBS. Molecular subtyping of several isolates identified 2 case patients in 1 NH with identical subtype patterns. NH residents have a markedly higher incidence of invasive GBS than do community residents > or = 65 years old and may serve as a target group for immunization when GBS vaccines become available. Further evaluation of intra-NH transmission of GBS is warranted.
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