Antibodies to Toxoplasma gondii in Individuals with First-Episode Schizophrenia | Zendy

Robert H. Yolken | Zendy; Silke Bachmann | Zendy; I. Rouslanova | Zendy; Erik P. Lillehoj | Zendy; G. C. Ford | Zendy; E. Fuller Torrey | Zendy; Johannes Schröeder | Zendy

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Antibodies to Toxoplasma gondii in Individuals with First-Episode Schizophrenia

Author(s) -

Robert H. Yolken,

Silke Bachmann,

I. Rouslanova,

Erik P. Lillehoj,

G. C. Ford,

E. Fuller Torrey,

Johannes Schröeder

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/319221

Subject(s) - toxoplasma gondii , schizophrenia (object oriented programming) , antibody , immunology , medicine , immunoassay , toxoplasmosis , autoantibody , blot , immunoglobulin g , psychiatry , biology , gene , genetics

We employed enzyme immunoassay (EIA) and Western blotting techniques to measure the level of antibodies to Toxoplasma gondii proteins in serum samples from 38 individuals undergoing their first episode of schizophrenia and from a group of matched control subjects. We found that the individuals with first-episode schizophrenia had significantly increased levels of IgG, IgM, and IgA class antibodies to Toxoplasma proteins, as compared with the control subjects.

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