Open AccessSevere Hepatic Injury Associated with Lipid Formulations of Amphotericin B
Author(s) -
Michael Ellis,
A. Shamoon,
W Gorka,
F. Zwaan,
Basel K. al-Ramadi
Publication year - 2001
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/319201
Subject(s) - amphotericin b , medicine , lipid a , necrosis , gastroenterology , pharmacology , surgery , antifungal , dermatology , lipopolysaccharide
A 14-year-old girl with leukemia had Doppler ultrasound evidence of hepatic necrosis, thought to be caused by a lipid formulation of amphotericin B, which has not been previously reported. It seems prudent to exert caution when retreating patients with previous hepatocellular damage with lipid formulations of amphotericin B.
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