Sporadic Inclusion Body Myositis in a Patient with Human T Cell Leukemia Virus Type 1-Associated Myelopathy | Zendy

S Ozden | Zendy; Antoine Gessain | Zendy; Olivier Gout | Zendy; J Mikol | Zendy

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Sporadic Inclusion Body Myositis in a Patient with Human T Cell Leukemia Virus Type 1-Associated Myelopathy

Author(s) -

S Ozden,

Antoine Gessain,

Olivier Gout,

J Mikol

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/318506

Subject(s) - medicine , myelopathy , pathogenesis , polymyositis , inclusion body myositis , leukemia , pathology , etiology , myositis , virus , virology , in situ hybridization , immunology , messenger rna , gene , biology , spinal cord , biochemistry , psychiatry

Sporadic inclusion body myositis is a disease of unknown pathogenesis in which a viral etiology has long been suspected. We report a case that occurred in a patient with human T cell leukemia virus type 1-associated myelopathy. The diagnosis was confirmed by histopathological studies of the deltoid muscle. Nucleic acids amplification and in situ hybridization indicated the presence of integrated proviral DNA and viral mRNA transcripts in the lesions.

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