Immunogenicity of Pneumococcal Vaccine in Heart Transplant Recipients | Zendy

Emily A. Blumberg | Zendy; Susan C. Brozena | Zendy; Patricia Stutman | Zendy; D. Wood | Zendy; Hoang M. Phan | Zendy; Daniel M. Musher | Zendy

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Immunogenicity of Pneumococcal Vaccine in Heart Transplant Recipients

Author(s) -

Emily A. Blumberg,

Susan C. Brozena,

Patricia Stutman,

D. Wood,

Hoang M. Phan,

Daniel M. Musher

Publication year - 2001

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/318482

Subject(s) - immunogenicity , medicine , pneumococcal vaccine , immunology , heart transplantation , antibody titer , pneumococcal polysaccharide vaccine , vaccination , pneumococcal infections , antibody , virology , titer , transplantation , streptococcus pneumoniae , pneumococcal disease , microbiology and biotechnology , biology , antibiotics

To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.

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