Cluster of Pulmonary Infections Caused byCunninghamella bertholletiaein Immunocompromised Patients | Zendy

Volker Rickerts | Zendy; Angelika Böhme | Zendy; Achim Viertel | Zendy; Gabriele Behrendt | Zendy; Volkmar Jacobi | Zendy; Kathrin Tintelnot | Zendy; G. JustNübling | Zendy

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Cluster of Pulmonary Infections Caused byCunninghamella bertholletiaein Immunocompromised Patients

Author(s) -

Volker Rickerts,

Angelika Böhme,

Achim Viertel,

Gabriele Behrendt,

Volkmar Jacobi,

Kathrin Tintelnot,

G. JustNübling

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/318144

Subject(s) - medicine , itraconazole , mucormycosis , zygomycosis , antifungal , dermatology , chemotherapy , amphotericin b , surgery

Cunninghamella bertholletiae is a rare cause of pulmonary mucormycosis. We describe a cluster of invasive pulmonary infections caused by C. bertholletiae in 4 immunocompromised patients that occurred during a 2-year period at 1 center. Three of the patients were receiving antifungal prophylaxis with itraconazole. Presenting symptoms were fever unresponsive to antibacterial chemotherapy, hemoptysis, and infiltrates on chest radiograms. Three patients were treated with liposomal amphotericin B. Only 1 patient survived.

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