Diagnostic Implications and Clinical Consequences of Antipyretic Therapy | Zendy

Philip A. Mackowiak | Zendy

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Diagnostic Implications and Clinical Consequences of Antipyretic Therapy

Author(s) -

Philip A. Mackowiak

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/317512

Subject(s) - antipyretic , medicine , nonsteroidal , intensive care medicine , altered mental status , acute illness , fever of unknown origin , pediatrics , analgesic , psychiatry

It has been suggested that the response to antipyretic therapy might differentiate between fevers due to serious illness and fevers caused by less severe disorders; that neoplastic fevers are more responsive to nonsteroidal anti-inflammatory drugs than are infectious fevers; that the metabolic costs of fever can exceeds its clinical benefits; that antipyretic therapy can prevent or reverse febrile seizures in children and fever-associated mental dysfunction in frail elderly patients. This article examines the data on which these assertions are based.

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