Incidence of Imipenem Hypersensitivity Reactions in Febrile Neutropenic Bone Marrow Transplant Patients with a History of Penicillin Allergy | Zendy

Scott A. McConnell | Zendy; Scott Penzak | Zendy; T. Scott Warmack | Zendy; E. Anaissie | Zendy; Paul O. Gubbins | Zendy

Open Access

Incidence of Imipenem Hypersensitivity Reactions in Febrile Neutropenic Bone Marrow Transplant Patients with a History of Penicillin Allergy

Author(s) -

Scott A. McConnell,

Scott Penzak,

T. Scott Warmack,

E. Anaissie,

Paul O. Gubbins

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/317507

Subject(s) - medicine , imipenem , penicillin , incidence (geometry) , allergy , antibiotics , hypersensitivity reaction , imipenem/cilastatin , immunology , microbiology and biotechnology , antibiotic resistance , physics , optics , biology

The purpose of this retrospective study was to assess cross-hypersensitivity between imipenem/cilastatin and penicillin in patients with reported penicillin allergies. Medical records of febrile neutropenic, penicillin-allergic bone marrow transplant recipients who received imipenem/cilastatin treatment were retrospectively reviewed. The findings of this study indicate the incidence of cross-reactivity between imipenem/cilastatin and penicillin among patients with a history of penicillin allergy may be lower than previously reported.

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