Chlamydia pneumoniaeand Cardiovascular Disease: An Evolutionary Perspective on Infectious Causation and Antibiotic Treatment | Zendy

Paul W. Ewald | Zendy; Gregory Cochran | Zendy

Open Access

Chlamydia pneumoniaeand Cardiovascular Disease: An Evolutionary Perspective on Infectious Causation and Antibiotic Treatment

Author(s) -

Paul W. Ewald,

Gregory Cochran

Publication year - 2000

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/315602

Subject(s) - chlamydia , causation , disease , infectious disease (medical specialty) , antibiotic resistance , biology , immunology , antibiotics , intensive care medicine , medicine , genetics , pathology , political science , law

Evolutionary considerations implicate infectious causation of atherosclerosis and help to resolve different risk factors as parts of an overall process of disease causation. An evolutionary approach also provides insight for the timing of research efforts to provide better control of pathogen evolution. In particular, evolutionary considerations emphasize the need to understand the transmissibility of Chlamydia pneumoniae from systemic infections in order to control the evolution of antibiotic resistance.

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