Prevalence and Molecular Epidemiology of Glycopeptide‐Resistant Enterococci in Belgian Renal Dialysis Units | Zendy

P. Descheemaeker | Zendy; M. Ieven | Zendy; Sabine Chapelle | Zendy; Christine Lammens | Zendy; M. Hauchecorne | Zendy; M. Wijdooghe | Zendy; Peter Vandamme | Zendy; Herman Goossens | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Prevalence and Molecular Epidemiology of Glycopeptide‐Resistant Enterococci in Belgian Renal Dialysis Units

Author(s) -

P. Descheemaeker,

M. Ieven,

Sabine Chapelle,

Christine Lammens,

M. Hauchecorne,

M. Wijdooghe,

Peter Vandamme,

Herman Goossens

Publication year - 2000

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/315182

Subject(s) - microbiology and biotechnology , enterococcus faecalis , dialysis , glycopeptide , epidemiology , enterococcus , gentamicin , molecular epidemiology , biology , enterococcus faecium , ampicillin , population , medicine , antibiotics , staphylococcus aureus , bacteria , genetics , genotype , gene , environmental health

The molecular epidemiology of glycopeptide-resistant enterococci (GRE) colonizing the intestinal tracts of Belgian renal dialysis patients was studied among 1318 patients of a population of 1800 dialysis patients from 29 dialysis centers. Of these, 185 patients (14.0%) were colonized with a VANA-positive GRE; GRE harboring the VANB gene were not detected. The majority of the VANA GRE (80.5%) were identified as Enterococcus faecium; 14.8% were identified as E. faecalis; and a limited number were identified as E. avium, E. casseliflavus, E. dispar, E. durans, or E. gallinarum. Genome analysis of 277 VANA-positive GRE by pulsed-field gel electrophoresis revealed a high genetic variability both within the different dialysis centers and within the patients' own GRE flora. No high-level gentamicin-resistant VANA-positive GRE were detected, and most strains remained susceptible to ampicillin. These findings do not support a hospital-driven endemicity of VANA-positive enterococcal isolates in Belgium.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research