Molecular Evidence of Ocular Epstein-Barr Virus Infection
Author(s) -
Karen S. Slobod,
J T Sandlund,
P. H. Spiegel,
Barrett G. Haik,
J L Hurwitz,
Mary Ellen Conley,
Laura C. Bowman,
E Benaim,
Jesse J. Jenkins,
Rose Mary S. Stocks,
Yanjun Gan,
John W. Sixbey
Publication year - 2000
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/313932
Subject(s) - medicine , virus , epstein–barr virus , disease , herpesviridae , gammaherpesvirinae , virology , in situ hybridization , epstein–barr virus infection , biopsy , viral disease , genome , virus isolation , pathology , immunology , gene , biology , genetics , gene expression
Ocular manifestations have been attributed to the Epstein-Barr virus (EBV), largely on the basis of seroepidemiologic data. Two patients who developed conjunctival disease as the presenting feature of EBV infection are reported, each confirmed by in situ hybridization of EBV genome in affected tissue biopsy specimens. Recognition of EBV-induced ocular disease as an initial presentation of clinical EBV infection is important to the practitioner because of the ubiquitous nature of this herpesvirus.
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